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TNFSF8 (tumor necrosis factor (ligand) superfamily, member 8 ) Blocking Peptide (the N terminal of TNFSF8)(100ug)

TNFSF8 (tumor necrosis factor (ligand) superfamily, member 8 ) Blocking Peptide (the N terminal of TNFSF8)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TNFSF8 Antibody (ARP63790_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63790
Size: 100ug
Weight: 26kDa
Gene: 944
Format: Lyophilized powder
Target: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Alternative names: CD153; CD30L; CD30LG; MGC138144
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