Reactivities: | Human |
Presku: | AAP59092 |
Size: | 100ug |
Weight: | 21kDa |
Gene: | 7292 |
Format: | Lyophilized powder |
Target: | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. |
Alternative names: | CD134L; CD252; GP34; OX-40L; OX4OL; TXGP1 |