
Supplier:
Aviva Systems Biology IncorporatedTNFRSF4 (tumor necrosis factor receptor superfamily, member 4) Blocking Peptide (the middle region of TNFRSF4)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP59086
Target
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Weight
27kDa
Gene Id
7293
Alternative Names
ACT35; CD134; OX40; TXGP1L
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