Reactivities: | Human |
Presku: | AAP63927 |
Size: | 100ug |
Weight: | 20kDa |
Gene: | 608 |
Format: | Lyophilized powder |
Target: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. |
Alternative names: | BCM; BCMA; CD269 |