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TNFRSF11B (tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)) Blocking Peptide (100ug)

TNFRSF11B (tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)) Blocking Peptide (100ug)

This is a synthetic peptide designed for use in combination with anti-TNFRSF11B antibody (Catalogue #: AVARP00033_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP30520

Target

TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Weight

46kDa

Gene Id

4982

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