TNFRSF10B Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Supplier: Aviva Systems Biology Incorporated

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Partial length TNFRSF10B is expressed in E. coli.

Presku:	APL10442
Size:	200ug
Weight:	40
Gene:	8795
Target:	The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Alternative names:	DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5