TNF Antibody (AMM00037)

Supplier: Aviva Systems Biology Incorporated

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This is a mouse monoclonal antibody raised by using full-length human TNF alpha protein. It was tested on ELISA and WB

Reactivities:	Human
Hosts:	Mouse
Applications:	Western Blot
Presku:	AMM00037
Size:	100ug
Weight:	26kDa
Gene:	7124
Format:	Lyophilized powder
Target:	TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Isotype:	Mouse IgG
Alternative names:	APC1 protein; TNF superfamily; member 2; TNF; macrophage-derived; monocyte-derived; TNF-a; cachectin; tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; DIF; TNFA; TNFSF2; TNF-alpha