Supplier:
Aviva Systems Biology IncorporatedTNF Antibody (AMM00037)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Applications
WB
Hosts
Mouse
Reactivities
Hum
Format
Lyophilized powder
Presku
AMM00037
Target
TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Weight
26kDa
Gene Id
7124
Isotype
Mouse IgG
Alternative Names
APC1 protein; TNF superfamily; member 2; TNF; macrophage-derived; monocyte-derived; TNF-a; cachectin; tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; DIF; TNFA; TNFSF2; TNF-alpha
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