TNF Antibody (AMM00036)

This is a mouse monoclonal antibody raised by using full-length human TNF alpha protein. It was tested on ELISA and WB

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SPECIFICATIONS

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum

Format

Lyophilized powder

Presku

AMM00036

Target

TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Weight

26kDa

Gene Id

7124

Isotype

Mouse IgG

Alternative Names

APC1 protein; TNF superfamily; member 2; TNF; macrophage-derived; monocyte-derived; TNF-a; cachectin; tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; DIF; TNFA; TNFSF2; TNF-alpha