Presku: | AAP58728 |
Size: | 100 ug |
Weight: | 24kDa |
Gene: | 10972 |
Format: | Lyophilized powder |
Target: | TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. |
Alternative names: | P24(DELTA); S31I125; S31III125; TMP21; Tmp-21-I |