Presku: | AAP32359 |
Size: | 100 ug |
Weight: | 83kDa |
Gene: | 7088 |
Format: | Lyophilized powder |
Target: | TLE1 is a transcriptional corepressor that binds to a number of transcription factors. TLE1 inhibits NF-kappa-B-regulated gene expression and the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. TLE1 has an unusual function as coactivator for ESRRG. |
Alternative names: | ESG; ESG1; GRG1 |