Reactivities: | Human |
Presku: | AAP59183 |
Size: | 100ug |
Weight: | 22kDa |
Gene: | 7078 |
Format: | Lyophilized powder |
Target: | This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. |
Alternative names: | HSMRK222; K222; K222TA2; SFD |