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TIMP-3 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251898

TIMP-3 Antibody

Tissue inhibitor of metalloproteinases 3 comple, Xenopus/Amphibian,es with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. TIMP-3 is critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian,. Defects in TIMP-3 are the cause of Sorsby fundus dystrophy (SFD). SFD is a rare autosomal dominant macular disorder with an age of onset in the fourth decade. It is characterized by loss of central vision from subretinal neovascularization and atrophy of the ocular tissues. Generally,Mouse,acular disciform degeneration develops in the patient

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SPECIFICATIONS

Catalog Number

251898

Size

0.1 mg

Applications

WB

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TIMP-3.

Isotype

Rabbit Ig

Accession

P35625

Additional Info

Metalloproteinase inhibitor 3; Tissue inhibitor of metalloproteinases 3; TIMP-3; Protein MIG-5; TIMP3

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