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Thyroid Hormone Receptor alpha2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253229

Thyroid Hormone Receptor alpha2 Antibody

Thyroid hormones are essential for development of the central nervous system. Deficits in these hormones during development affect cognitive functions as learning and memory. Thyroid hormones e, Xenopus/Amphibian,ert their physiological role mainly through binding to specific nuclear receptors including the predominant isoforms of thyroid hormone receptors TRa1, TRa2, TRb1 and TRb2. TRa1, TRb1 and TRb2 bind T3 with high affinity and also bind to thyroid hormone response elements (TREs) on chromatin to regulate the transcriptional processes in several target tissues, including adult rat brain.

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SPECIFICATIONS

Catalog Number

253229

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Bov, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

KLH-conjugated peptide encompassing a sequence within the N-term region of human thyroid hormone receptor, a2-isotype.

Isotype

Mouse IgG1

Accession

P10827

Clonality

1330

Additional Info

Nuclear receptor subfamily 1 group A member 1; V-erbA-related protein 7; EAR-7; c-erbA-1; c-erbA-alpha

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