Reactivities: | Human |
Presku: | AAP63775 |
Size: | 100ug |
Weight: | 66kDa |
Gene: | 387357 |
Format: | Lyophilized powder |
Target: | THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
Alternative names: | C6orf190; C6orf207; FLJ40584; MGC163388; TSEPA; bA325O24.3; bA325O24.4 |