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TGF-beta Receptor Type II Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250880

TGF-beta Receptor Type II Antibody

TGF-beta receptor type II (TGFR2) forms a heteromeric comple, Xenopus/Amphibian, with TGFR1 after binding TGF-beta at the cell surface and activates TGFR2 by phosphorylation, subsequently binding and activation of the SMAD transcriptional regulators. Defects in TGFR2 are a cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6), esophageal cancer, and Loeys-Dietz syndromes (aortic aneurism syndrome).

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SPECIFICATIONS

Catalog Number

250880

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGFR2.

Isotype

Rabbit Ig

Accession

P37173

Additional Info

TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TGF-beta type II receptor; TbetaR-II; TGFR-2; TGFBR2

SUPPLIER INFO

ABBIOTEC

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