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TGF-beta Receptor Type II Antibody

TGF-beta Receptor Type II Antibody

Cat no: 250880

Supplier: ABBIOTEC
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TGF-beta receptor type II (TGFR2) forms a heteromeric comple, Xenopus/Amphibian, with TGFR1 after binding TGF-beta at the cell surface and activates TGFR2 by phosphorylation, subsequently binding and activation of the SMAD transcriptional regulators. Defects in TGFR2 are a cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6), esophageal cancer, and Loeys-Dietz syndromes (aortic aneurism syndrome).
Catalogue number: 250880
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P37173
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGFR2.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TGF-beta type II receptor; TbetaR-II; TGFR-2; TGFBR2
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