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TGF-beta Receptor Type I Antibody

TGF-beta Receptor Type I Antibody

Cat no: 250879

Supplier: ABBIOTEC
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TGF-beta receptor type I (TGFR1) forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors that autophosphorylate and activate SMAD transcriptional regulators. Although TGFR1 is ubiquitously e, Xenopus/Amphibian,pressed, it is found most abundant in placenta and least abundant in brain and heart. Defects in TGFBR1 are the cause of Loeys-Dietz syndrome type 1 and 2 (aortic aneurysm syndromes).
Catalogue number: 250879
Reactivities: Human, Mouse
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P36897
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGFR1.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: TGF-beta receptor type-1; Transforming growth factor-beta receptor type I; TGF-beta receptor type I; TGF-beta type I receptor; TbetaR-I; TGFR-1; Serine/threonine-protein kinase receptor R4; SKR4; Activin receptor-like kinase 5; ALK5; TGFBR1
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