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TFRC (transferrin receptor (p90, CD71) ) Blocking Peptide (the N terminal of TFRC)(100ug)

TFRC (transferrin receptor (p90, CD71) ) Blocking Peptide (the N terminal of TFRC)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TFRC Antibody (ARP63719_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP63719
Size: 100ug
Weight: 84kDa
Gene: 7037
Format: Lyophilized powder
Target: TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Alternative names: CD71; TFR; TFR1; TRFR
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