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TFEC (Human) cDNA (1ug)

TFEC (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human TFEC is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-TFEC polyclonal antibody.
Presku: ANA10564
Size: 1ug
Gene: 22797
Target: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form.
Alternative names: TCFEC; TFECL; bHLHe34; TFE-C; TFEC-L; hTFEC-L
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