Presku: | AAP31073 |
Size: | 100 ug |
Weight: | 57kDa |
Gene: | 7024 |
Format: | Lyophilized powder |
Target: | TFCP2 binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. It also functions as part of the SSP (stage selector protein) complex. TFCP2 facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. It interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. |
Alternative names: | CP2; LBP-1C; LSF; SEF; TFCP2C |