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TFB2M (transcription factor B2, mitochondrial) Blocking Peptide (100ug)

TFB2M (transcription factor B2, mitochondrial) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TFB2M antibody (Catalogue #: ARP39550_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP39550
Size: 100 ug
Weight: 45kDa
Gene: 64216
Format: Lyophilized powder
Target: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alternative names: FLJ22661; FLJ23182; Hkp1
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