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Products TFAP2B Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)
| Presku: | APL10540 |
| Size: | 200ug |
| Gene: | 7021 |
| Target: | This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives. |
| Alternative names: | AP-2B; AP2-B; MGC21381 |
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