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TFAP2B (Human) cDNA (1ug)

TFAP2B (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human TFAP2B is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-TFAP2B polyclonal antibody.
Presku: ANA10540
Size: 1ug
Gene: 7021
Target: This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
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