Supplier:
Aviva Systems Biology IncorporatedTFAP2A antibody - C-terminal region (P100878_T100)
Prices direct from Aviva Systems Biology Incorporated
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SPECIFICATIONS
Size
100ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov, Ch/Bird, Prc
Format
Lyophilized powder
Presku
P100878_T100
Target
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM].
Weight
48kDa
Gene Id
7020
Alternative Names
AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
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