Home  >  Products  >  TDP43 Antibody
TDP43 Antibody

TDP43 Antibody

Cat no: 253225


Supplier: ABBIOTEC
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
TAR DNA-binding protein 43 (TDP-43) is a DNA and RNA-binding protein which regulates transcription and splicing. TDP-43 is involved in the regulation of CFTR splicing, and promotes CFTR e, Xenopus/Amphibian,on 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this e, Xenopus/Amphibian,on. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TDP-43 is also involved in microRNA biogenesis, apoptosis, and cell division. TDP-43 can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Catalogue number: 253225
Reactivities: Human, Rabbit
Applications: Immunohistochemistry
Size: 0.1 ml
Accession: Q13148
Antigen: KLH-conjugated peptide encompassing a sequence within the C-term region of human TDP43.
Format: Each vial contains 0.1 ml IgG in PBS pH7.4, 30% glycerol with 0.065% sodium azide. Antibody was purified byimmunogen affinity precipitation.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: TDP-43; TARDBP; TAR DNA-binding protein 43; TDP43