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TDP-43 Antibody

TDP-43 Antibody

Cat no: 251318

Supplier: ABBIOTEC
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TAR DNA-binding protein 43 (TDP-43) is a DNA and RNA-binding protein which regulates transcription and splicing. TDP-43 is involved in the regulation of CFTR splicing, and promotes CFTR e, Xenopus/Amphibian,on 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this e, Xenopus/Amphibian,on. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TDP-43 is also involved in microRNA biogenesis, apoptosis, and cell division. TDP-43 can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Catalogue number: 251318
Reactivities: Human, Mouse, Bovine, Chicken/Bird, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q13148
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TDP-43.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: TDP-43; TARDBP; TAR DNA-binding protein 43; TDP43
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