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TCHP (trichoplein, keratin filament binding) Blocking Peptide (the C terminal of TCHP)(100ug)

TCHP (trichoplein, keratin filament binding) Blocking Peptide (the C terminal of TCHP)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-TCHP Antibody (ARP60515_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP60515
Size: 100ug
Weight: 61kDa
Gene: 84260
Format: Lyophilized powder
Target: TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Alternative names: MGC10854
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