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TCF-4 Antibody

TCF-4 Antibody

Cat no: 251642

Supplier: ABBIOTEC
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T-cell-specific transcription factor 4 (TCF-4) participates in the Wnt signaling pathway and modulates MYC e, Xenopus/Amphibian,pression by binding to its promoter in a sequence-specific manner. TFC-4 acts as repressor in the absence of CTNNB1, and as activator in its presence. TCF-4 is necessary for the maintenance of the epithelial stem-cell compartment of the small intestine. Genetic variations in TCF-4 are associated with susceptibility to non-insulin-dependent diabetes mellitus (NIDDM). NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.
Catalogue number: 251642
Reactivities: Human, Mouse, Porcine, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: Q9NQB0
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TCF-4.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: Transcription factor 7-like 2; HMG bo, Xenopus/Amphibian, transcription factor 4; T-cell-specific transcription factor 4; T-cell factor 4; TCF-4; hTCF-4; TCF7L2; TCF4
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