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TARDBP (Human) cDNA (1ug)

TARDBP (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human TARDBP is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-TARDBP polyclonal antibody.
Presku: ANA10923
Size: 1ug
Gene: 23435
Target: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Alternative names: ALS10; TDP-43
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