Supplier:
Aviva Systems Biology IncorporatedTAPBP (TAP binding protein (tapasin)) Blocking Peptide (the N terminal of TAPBP)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP45436
Target
TAPBP is a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum.
Weight
30kDa
Gene Id
6892
Alternative Names
NGS17; TAPA; TPN; TPSN
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