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Taf1c (TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C) Blocking Peptide (the C terminal of Taf1c)(100ug)

Taf1c (TATA box binding protein (Tbp)-associated factor, RNA polymerase I, C) Blocking Peptide (the C terminal of Taf1c)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-Taf1c Antibody(ARP40130_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Mouse
Presku: AAP40130
Size: 100ug
Weight: 92kDa
Gene: 21341
Format: Lyophilized powder
Target: Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Alternative names: Tafi95; mTAFI95
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