Presku: | AAP38668 |
Size: | 100 ug |
Weight: | 85kDa |
Gene: | 9013 |
Format: | Lyophilized powder |
Target: | Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. TAF1C is the largest SL1-specific TAF. |