Reactivities: | Human, Rat |
Presku: | AAP37302 |
Size: | 100ug |
Weight: | 49kDa |
Gene: | 360893 |
Format: | Lyophilized powder |
Target: | Taf1a is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. |