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SYVN1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 200108

SYVN1 Antibody

Synoviolin (SYVN1) acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates subsequently promoting their degradation. For instance, SYVN1 protects neurons from apoptosis induced by polyglutamine-e, Xenopus/Amphibian,panded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. SYVN1 is up-regulated in synovial tissues from patients with rheumatoid arthritis.

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SPECIFICATIONS

Catalog Number

200108

Size

0.1 mg

Applications

WB

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SYVN1.

Isotype

Rabbit Ig

Accession

Q86TM6, NP_115807

Additional Info

E3 ubiquitin-protein ligase synoviolin; Synovial apoptosis inhibitor 1; HRD1; SYVN1

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