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Synapsin I (Ser9) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252580

Synapsin I (Ser9) Antibody

Synapsin I plays a key role in synaptic plasticity in brain. This effect is due in large part to the ability of the synapsins to regulate the availability of synaptic vesicles for release. In addition to its role in plasticity, the e, Xenopus/Amphibian,pression of synapsin I is a precise indicator of synapse formation. Thus, synapsin I immunocytochemistry provides a valuable tool for the study of synaptogenesis. The role of synapsin in synaptic plasticity and in synaptogensis is regulated by phosphorylation. Serine 9 is the site on synapsin I that is phosphorylated by cAMP-dependent protein kinase and by calcium calmodulin kinase I. Phosphorylation of this site is thought to regulate synaptic vesicle function and neurite outgrowth. \n

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SPECIFICATIONS

Catalog Number

252580

Size

0.1 ml

Applications

IHC

Reactivities

Hum, Mouse, Bov, Rabbit, Xen/Amph, ZF/Fish

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser9 of rat synapsin-1.

Isotype

Rabbit IgG

Accession

P17599

Additional Info

Synapsin-1; Synapsin I; SYN1

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