Presku: | AAP46214 |
Size: | 100 ug |
Weight: | 69kDa |
Gene: | 23075 |
Format: | Lyophilized powder |
Target: | Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion. |
Alternative names: | FLJ39540; HSPC321; KIAA0640; SWAP-70 |