Presku: | AAP43058 |
Size: | 100 ug |
Weight: | 35kDa |
Gene: | 10273 |
Format: | Lyophilized powder |
Target: | STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. |
Alternative names: | CHIP; HSPABP2; NY-CO-7; SDCCAG7; UBOX1 |