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STK-10 (Ser482/486/490) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252573

STK-10 (Ser482/486/490) Antibody

Considerable evidence indicates that a polo-like kinase (PLK) plays an important role in cell cycle regulation. PLK is also required for bipolar spindle formation, activation of the anaphase-promoting comple, Xenopus/Amphibian,/cyclosome, and cytokinesis. Recent work led to the identification of a PLKK that is thought to be responsible for activation of PLK. Recent work has shown that PLKK is in turn activated by phosphorylation at three sites (Ser482, Ser486 and Ser490). Thus activation of PLK is thought to involve a kinase cascade involving the phosphorylation of Ser482,486,490 in PLKK.

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SPECIFICATIONS

Catalog Number

252573

Size

0.1 ml

Applications

WB

Reactivities

Hum, Mouse, Rabbit, Xen/Amph, ZF/Fish

Format

Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody

Antigen

KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser482/486/490 of , Xenopus/Amphibian,enopus polo-like kinase kinase.

Isotype

Rabbit IgG

Accession

P70032

Additional Info

Polo-like kinase kinase 1; stk10; , Xenopus/Amphibian,Plkk1

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