Presku: | AAP43536 |
Size: | 100 ug |
Weight: | 54kDa |
Gene: | 55240 |
Format: | Lyophilized powder |
Target: | AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT |
Alternative names: | STMP3; TSAP6; dudlin-2 |