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STEAP3 antibody - N-terminal region (ARP43536_T100)

STEAP3 antibody - N-terminal region (ARP43536_T100)

This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).

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SPECIFICATIONS

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Format

Lyophilized powder

Presku

ARP43536_T100

Target

AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT

Weight

54kDa

Gene Id

55240

Alternative Names

STMP3; TSAP6; dudlin-2

SUPPLIER INFO

Aviva Systems Biology Incorporated

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