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Products STAT6 Antibody (AMM00022)
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | Western Blot |
| Presku: | AMM00022 |
| Size: | 100ug |
| Weight: | 94kDa |
| Gene: | 6778 |
| Format: | Lyophilized powder |
| Target: | STAT6 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. |
| Isotype: | Mouse IgG |
| Alternative names: | STAT6B; STAT6C; D12S1644; IL-4-STAT |
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