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STAT5
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251511

STAT5

Signal transducer and activator of transcription 5A (STAT5) carries out a dual function: signal transduction and activation of transcription. STAT5 is tyrosine phosphorylated in response to IL-2, IL-3, IL-7, IL-15, GM-CSF, growth hormone,Porcinerolactin, erythropoietin and thrombopoietin. Phosphorylation results in translocation into the nucleus, where it binds to the GAS element and activates transcription. Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for ma, Xenopus/Amphibian,imal transcriptional activity.

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SPECIFICATIONS

Catalog Number

251511

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT5.

Isotype

Rabbit Ig

Accession

P42229

Additional Info

Signal transducer and activator of transcription 5A; STAT5A; STAT5

SUPPLIER INFO

ABBIOTEC

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