Presku: | AAP33376 |
Size: | 100 ug |
Weight: | 86kDa |
Gene: | 6775 |
Format: | Lyophilized powder |
Target: | STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. |