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STAT3 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251107

STAT3 Antibody

STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).

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SPECIFICATIONS

Catalog Number

251107

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT3.

Isotype

Rabbit Ig

Accession

P40763

Additional Info

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

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