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ST14 (suppression of tumorigenicity 14 (colon carcinoma)) Blocking Peptide (the middle region of ST14)(100ug)

ST14 (suppression of tumorigenicity 14 (colon carcinoma)) Blocking Peptide (the middle region of ST14)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-ST14 Antibody(ARP48057_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP48057
Size: 100ug
Weight: 95kDa
Gene: 6768
Format: Lyophilized powder
Target: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Alternative names: HAI; MT-SP1; MTSP-1; MTSP1; PRSS14; SNC19; TADG-15
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