Supplier:
Aviva Systems Biology IncorporatedST14 (suppression of tumorigenicity 14 (colon carcinoma)) Blocking Peptide (the middle region of ST14)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP48057
Target
ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Weight
95kDa
Gene Id
6768
Alternative Names
HAI; MT-SP1; MTSP-1; MTSP1; PRSS14; SNC19; TADG-15
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