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ST13 (3B10) Antibody
ABBIOTEC

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ABBIOTEC

Cat no: 252945

ST13 (3B10) Antibody

ST13 (Suppression of tumorigenicity protein 13) is one of several co-chaperones that regulate activities of the HSP70 chaperone family. ST13, also known as Hip (HSP70-interacting protein) cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, also controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

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SPECIFICATIONS

Catalog Number

252945

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum, Mouse

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human ST13 e, Xenopus/Amphibian,pressed in E. coli. \r<br>

Isotype

Mouse IgG1

Accession

P50502

Clonality

3B10

Additional Info

Hsc70-interacting protein; Hip; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; Suppression of tumorigenicity 13 protein; FAM10A1; HIP; SNC6; ST13

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