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SRSF1 (Human) cDNA (1ug)

SRSF1 (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human SRSF1 is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-SRSF1 polyclonal antibody.
Presku: ANA11117
Size: 1ug
Gene: 6426
Target: This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.
Alternative names: ASF; SF2; SFRS1; SF2p33; SRp30a; MGC5228; FLJ53078
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