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SPPL2B (signal peptide peptidase-like 2B) Blocking Peptide (100ug)

SPPL2B (signal peptide peptidase-like 2B) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SPPL2B antibody (Catalogue #: ARP44989_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP44989
Size: 100 ug
Weight: 56kDa
Gene: 56928
Format: Lyophilized powder
Target: SPPL2B is a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways.
Alternative names: IMP4; KIAA1532; MGC111084; PSL1
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