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SPI1 (spleen focus forming virus (SFFV) proviral integration oncogene spi1) Blocking Peptide (the middle region of protein) (100ug)

SPI1 (spleen focus forming virus (SFFV) proviral integration oncogene spi1) Blocking Peptide (the middle region of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-SPI1 antibody (Catalogue #: ARP38241_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP38241
Size: 100 ug
Weight: 31kDa
Gene: 6688
Format: Lyophilized powder
Target: SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative names: OF; PU.1; SFPI1; SPI-1; SPI-A
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