Supplier:
Aviva Systems Biology IncorporatedSPG20 (spastic paraplegia 20 (Troyer syndrome)) Blocking Peptide (the middle region of SPG20)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP55162
Target
This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Weight
73kDa
Gene Id
23111
Alternative Names
KIAA0610; SPARTIN; TAHCCP1
SUPPLIER INFO
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