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SORL1 (3B6B) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252723

SORL1 (3B6B) Antibody

SORL1 (Sortilin-related receptor, LA repeats containing) is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytosis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. SorLA is e, Xenopus/Amphibian,pressed mainly in brain (cerebral corte, Xenopus/Amphibian,, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.\r

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SPECIFICATIONS

Catalog Number

252723

Size

0.1 ml

Applications

IF, IHC

Reactivities

Hum

Format

Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.

P Type

Mouse Monoclonal Antibody

Antigen

Purified recombinant fragment of human SORL1 e, Xenopus/Amphibian,pressed in E. coli.

Isotype

Mouse IgG1

Accession

Q92673

Clonality

3B6B11

Additional Info

Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repeats; SorLA; SORL1; C11orf32

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